Cheesy Chicken Pasta Bake

Every piece of chicken and penne pasta is generously coated with Alfredo and cheeses while baking. This Cheesy Chicken Pasta Bake makes an easy casserole recipe that will make your taste buds smile!

Creamy and delicious chicken penne alfredo bake next to casserole dish on a red and white plaid napkin

If you enjoy this recipe you may also like our Spaghetti Pie or Tiktok Chicken Bacon Ranch Mac and Cheese!

Recipe For Penne Alfredo With Chicken

A trio of mozzarella, ricotta and parmesan cheeses add a depth to the already rich and creamy Alfredo, pasta, and chicken mixture that is the base of this recipe. 

The ridges on the cylindrical shaped penne pasta hold all of the cheesy Alfredo sauce that makes this recipe amazing. Pro tip – save a few noodles at the end to totally clean the cheesy chicken combo off your plate.

A layer of bread crumbs on top become toasted and lightly browned giving this dish the perfect finish. I could eat the top layer of mozzarella cheese with the Italian bread crumbs baked in as a meal!

Save this Recipe
Please enable JavaScript in your browser to complete this form.

Enter your email and I’ll send this recipe right to your inbox! Plus, I’ll send you new recipes every week!

Large serving spoon of alfredo and mozzarella cheese mixture pulling up away from casserole dish of cheesy chicken pasta bake

Also known as Three Cheese Chicken Alfredo Bake and Chicken Alfredo Casserole we enjoy how parsley adds fresh flavor and visual interest to a creamy white pasta casserole

Chicken can be added to our Baked Mostaccioli or Crock Pot Spaghetti, but we just like it the best white cheese and white sauce in this chicken Alfredo and penne combination.

Why This Chicken Pasta Bake Works:

  • Great for meal prep – casserole can be made ahead of time, refrigerated and bake when ready
  • Perfect meal to take to someone who just had a baby, lost a loved one or needs a pick-me-up
  • Even picky eaters love a simple cheese and pasta combination
  • Only 15 minutes of hands on time and 30 minutes in the oven before this meal is on the table
  • Can make a full batch, bake half now and freeze the other half for a quick meal later on
Serving spoon fully of creamy and cheesy chicken pasta bake laying on the edge of a large white baking dish

What Do you Eat with Penne Alfredo?

Tastes great served with slices of Garlic Texas Toast and a simple salad or roasted green vegetable like broccoli.

Ingredients Needed:

  • Penne pasta – creates the most filling part of this casserole – mostaccioli is similar in shape to penne rigate and works fine too
  • Cooked chicken – we like to shred a rotisserie chicken to save time, if the pieces are big coarsely chop them too
  • Alfredo sauce – a couple containers from the grocery store refrigerator section are our favorite as they are a little higher quality than a jar, but much easier than homemade
  • Mozzarella cheese – melts beautifully and gives that beautiful cheese pull every time you lift the serving spoon out of the dish
  • Ricotta cheese – fresh and creamy, this cheese gives more substance to the white sauce
  • Parmesan cheese – compliments the alfredo sauce so beautifully – sometimes my kids like to sprinkle more parmesan on top
  • Sour cream – more rich and moist flavors for the pasta to absorb in the baking process
  • Garlic cloves – adds a pop of aromatic flavor – the amount is easy to adjust to suite personal preference
  • Eggs – help thicken the creamy sauces and add a little richness
  • Parsley – fresh parsley brightens the look and flavor of this creamy pasta bake
  • Bread crumbs – we prefer Italian, but panko or regular work fine too – helps make a beautiful and lightly crunchy topping that I crave
Sour cream, mozzarella, eggs, penne, shredded chicken, minced garlic, ricotta, alfredo, parmesan and fresh parsley ingredients to make chicken pasta bake

How to Make This Chicken Pasta Bake

Cook the pasta to al dente according to the directions on the box using salted water.

Cook chicken if necessary or shred and chop a rotisserie chicken.

Preheat oven to 350°F.

In a large mixing bowl add 1 cup of mozzarella cheese, alfredo sauce, sour cream, ricotta cheese, garlic, lightly beaten eggs and parmesan cheese.

Alfredo sauce poured over cooked penne pasta with other cheeses

Stir until well mixed.

This takes a pretty large mixing bowl to contain all of the ingredients and give adequate space to mix well.

Penne pasta and alfredo mixture being stirred together in a large mixing bowl

Add cooked chicken.

Chicken on top of a mixing bowl full of alfredo penne mixture

Then add parsley and stir again.

Parsley in a mixing bowl of ingredients for cheesy chicken alfredo bake

Lightly coat a 9 x 13 dish with non-stick cooking spray.

Once mixed spread in casserole dish.

Cheesy and creamy chicken and pasta mixture spread in a 9 x 13" baking dish

Sprinkle remaining 2 cups of mozzarella cheese over the top.

Then sprinkle bread crumbs.

Shredded mozzarella and bread crumbs on top top of a yummy chicken alfredo casserole

Bake uncovered for 30 to 40 minutes until the edges are bubbly and the top starts to get golden brown.

Serve warm and enjoy!

Chicken Penne Alfredo Recipe Tips & Tricks

  • Can use fresh or dried basil in place of parsley 
  • Using a rotisserie chicken saves so much time
  • Reducing from 3 cups of chicken to 1 to 2 cups would be fine because the dairy products are so satisfying
  • Add slices of Kielbasa for a deeper complimentary meat flavor
  • I love the lightly browned layer of mozzarella cheese and bread crumbs on top, but if you prefer an all creamy meal then stir the mozzarella in and bake covered with foil
  • A cup or two of fresh baby spinach enhances this pasta recipe with more vegetables
  • Can use homemade Alfredo, a jar or a refrigerated container which is our favorite
Plate full of delicious three cheese chicken alfredo bake on a small white plate next to the casserole dish full

Do You Cook Pasta Before Baking?

The pasta in this baked pasta dish should be cooked al dente before baking. The pasta will soften a little bit in the oven and absorb some of the extra liquid in the dish. Baking is more about melting the cheese and warming everything together.

What Type of Pasta is Best for Pasta Bake?

Penne pasta is great for this baked casserole because the surface area helps scoop up the cheesy, creamy, meaty mixture all around it.

Should Pasta Be Baked Covered or Uncovered?

When baked uncovered the top will get a little brown and slightly toasted which is perfect when using breadcrumbs. 

Covering the dish with foil keeps the pasta bake soft and creamy. Bread crumbs are not recommended if this is the preferred finish.

Over head view of toasted bread crumbs and melted mozzarella cheese on chicken alfredo bake with a large silver spoon stirring up the corner

More Easy Meals with Pasta

Pizza Casserole is great with noodles or pasta as the crust and is so easy to make.

Crock Pot Chicken Parmesan makes a classic dish with spaghetti all in the slow cooker.

Easy Crock Pot Mac & Cheese is so simple and always popular at holidays and big family meals.

Cheesy Chicken Pasta with Velveeta Casserole has a bag of frozen Italian veggies and can of rotel for an easy twist that’s enjoyable.

Close up penne pasta covered in a creamy alfredo and white cheese mixture with shredded chicken and parsley showing around some of the pasta on a white plate with a fork in the background

Cheesy Chicken Pasta Bake

Servings 8 servings
Author: Jennifer
Every piece of chicken and penne pasta is generously coated with Alfredo and cheeses while baking. This Cheesy Chicken Pasta Bake makes an easy casserole recipe that will make your taste buds smile!
Prep Time 15 minutes
Cook Time 35 minutes
Total Time 50 minutes

Ingredients
  

  • 16 ounces penne pasta
  • 32 ounces Alfredo sauce
  • 3 cups chicken cooked and chopped
  • 3 cups Mozzarella cheese divided
  • 1/4 cup parmesan cheese
  • 15 ounces ricotta cheese
  • 8 ounces sour cream
  • 2 garlic cloves minced
  • 2 eggs slightly beaten
  • 1/4 cup fresh parsley
  • 1/3 cup Italian bread crumbs

Instructions
 

  • Preheat oven to 350°F.
  • Prepare pasta, drain and return to the pot if it is large enough to stir everything together, otherwise use a large mixing bowl.
  • Add to the pasta 1 cup of mozzarella cheese, Alfredo, sour cream, ricotta, parmesan, sour cream, garlic, and lightly beaten eggs. Stir well.
  • Add chicken and parsley and stir well.
  • Pour mixture into a lightly greased 9 x 13" baking dish.
  • Sprinkle remaining mozzarella cheese on top. Then top with bread crumbs.
  • Bake for 30 – 40 minutes until casserole is bubbly around the edges, cheese is melted and beginning to become lightly brown on top.

Nutrition

Calories: 782kcalCarbohydrates: 54gProtein: 34gFat: 46gSaturated Fat: 24gPolyunsaturated Fat: 7gMonounsaturated Fat: 13gTrans Fat: 0.02gCholesterol: 210mgSodium: 1230mgPotassium: 331mgFiber: 2gSugar: 5gVitamin A: 977IUVitamin C: 3mgCalcium: 421mgIron: 2mg

Nutritional Disclaimer

“Plowing Through Life” is not a dietitian or nutrition professional. Any nutritional information shared is an estimate and can vary greatly depending on specific products are used. If calorie count and other nutritional values are important to you, we recommend running the ingredients through an online nutritional calculator of your choice.

Tried this recipe?Mention @PlowingThroughLife or tag #PlowingThroughLife!

Leave a Reply

Your email address will not be published. Required fields are marked *

Recipe Rating